Thank you letter from Run for Her


We recently received a thank you letter from Run for Her for our $20,000 contribution. We are pleased to be able to donate to this worthy event. If you would like more info on Run for Her click here.
Sincerely,
Sharon Leigh

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Grant from PG&E


The Sharon Leigh Ovarian Cancer Foundation recently received a grant from Pacific Gas and Electric. We are very excited, not only about the funds they have donated to further research into Ovarian Cancer research but also because of the recognition they provide. We are very pleased that this corporation has acknowledged our work as beneficial and that they recognize the hours and hours of work that our organization has devoted to education about, and prevention of Ovarian Cancer.

Our sincere thanks to PG&E for their generous donation, together we are making a difference in the battle against Ovarian Cancer.
Sincerely,
Sharon Leigh

Note: if you or your company would like to join us in our efforts click here.

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Fashion Show in Oceano, California

Luncheon & Fashion Show
The Sharon Leigh Ovarian Cancer Foundation Teal Magnolia's Luncheon & Fashion Show on Saturday, January 17th was a huge success, with a sold out capacity!

Le Papillion in the Village of Arroyo Grande Ca. partnered with the Sharon Leigh Ovarian Cancer Foundation with models and beautiful clothing for everyday and evening. Guest speakers were Cristina Martins Sinco & Sharon Leigh. Cristina spoke on signs to look for regarding Ovarian cancer. Sharon shared on the deadly Braca gene which can lead to both breast and ovarian cancer..

The Fashion Show and Ovarian Cancer awareness luncheon was held at the Elks Lodge in Oceano California and the Elks Lodge fully sponsored this great event, knowing full well the dangers of this terrible disease they did not hesitate to offer their support. They prepared Chicken wraps, salad and fruit in season for our lunch it was delightful. We are so grateful to them as this was the first event (of many to come) specifically designed to meet our goal of furthering education on early detection of Ovarian cancer. We have other events such as this one planned.

Sharon Leigh Ovarian cancer foundation is a non- profit is 501( c ) 3
Ticket printing for this event sponsored by Sierra Auto, Grover Beach Ca.
Posters sponsored by SLCO Data, Grover Beach.


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Starting the Amgen Tour

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Starting the Amgen Tour
May 3rd, 2014

I am very excited to get the opportunity to start Stage 5 of the local 2014 Amgen Tour of California! Amgen's program "Breakaway from Cancer®" initiative, aims to increase awareness of the important resources available to people affected by cancer—from prevention through survivorship.

Stage 5 of the race starts on Thursday, May 15th. Click here to read more about this exciting race.

Sincerely,
Sharon



684 Women A Day

684 WOMEN PER DAY ARE DIAGNOSED WITH OVARIAN CANCER
This is not a feel good article...

Unbelievable, just think of this 75% of these women will not live past 5 years, that is 513 women. I'm having a problem writing this as these figures are astonishing. 24,966 women per year diagnosed with Ovarian Cancer. With a mortality rate at 75%.

It's time to educate, get the word out, help women become their own advocate. Let's catch this disease in the early stages where we can read more survivor stories, not obituaries.

This (and any type of cancer) doesn’t just affect one person, it affects the entire family and close friends, our childhood best friends, we all suffer.

Cancer is wide spread, asking for an end to cancer is wonderful, that's just not as realistic as we would want it to be. But early detection is within our reach. Get all of the information you can, and it's free. The CDC and National Cancer organizations will happily donate information, brochures anything you might need if you are ready to start the fight.

I started my own foundation which is literally a grass roots organization with that one goal I'm sure you have, help others as you were helped. Reach out into the community and you will be surprised at the response you'll get. Find a hospital that has a research center, join forces with them. I reached out to Cedars-Sinai in Los Angeles, we have been partners for 3 years now. If I could do it so can you.

Contact me for more info at: This email address is being protected from spambots. You need JavaScript enabled to view it.

Sincerely,
Sharon

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10 genes

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Guest Report from Jacqueline Vitti Frederick
March 10th, 2014

This study was done at the hospital where my daughter was treated for ovarian cancer. This is why we need to continue to fundraise and support ongoing research. It will save lives.

Kathy Boltz, PhD
December 23, 2013
Genetic biomarker for ovarian cancer deepens knowledge of survival outcomes

A series of 10 genes have been identified that may signify a trifecta of benefits for women with ovarian cancer. This 10-gene biomarker panel may identify the aggressiveness of a patient's disease, help predict survival outcomes, and result in novel therapeutic strategies tailored to patients with the most adverse survival outcomes.

When a patient's tumor is identified as having elevated levels of these 10 specific genes, doctors may be able to better predict which treatments would be most effective, said Dong-Joo (Ellen) Cheon, PhD, of the Women's Cancer Program at Cedars-Sinai's Samuel Oschin Comprehensive Cancer Institute in Los Angeles, California. The research was published in Clinical Cancer Research (2013; doi:10.1158/1078-0432.CCR-13-1256).

That is an important advance because ovarian cancer is the most lethal gynecologic cancer and is often diagnosed in later, more aggressive stages, resulting in poor prognosis and survival. These outcomes differ due to development of tumors that become resistant to chemotherapy. By identifying chemo-resistant tumors and identifying the risk of poor survival outcomes during the diagnostic process, investigators hope to extend lives and improve treatment responses for women with ovarian cancer.

"The ultimate goal is to use the 10-gene biomarker panel to develop a diagnostic kit that will identify patients with the most adverse outcome and provide targeted therapeutic strategies," said Cheon. "Among the biomarkers identified, the gene COL11A1 was shown to be the most abundantly expressed in ovarian cancer progression. But when we blocked expression of COL11A1 in murine cancer cells, tumor growth and spread was significantly reduced."

The 10-gene biomarker panel revealed another promising benefit. The 10 genes associated with the panel all share one common biological process—the formation of a collagen matrix around cancerous cells. This thick, collagen-rich matrix can protect cancer cells from the lethal effect of chemotherapy and serve as an incubator for increasingly aggressive cancer cells. Understanding how this collagen-rich environment may contribute to aggressive tumor cell behavior may ultimately lead to more efficient therapies.

"This data, based on the analysis of nearly 800 ovarian cancer patients, suggests that patients who have elevated levels of genes associated with the biomarker panel have shorter survival and more aggressive forms of disease," said Sandra Orsulic, PhD, senior author of this study, and director of women's cancer biology in the Women's Cancer Program, and associate professor in the Department of Obstetrics and Gynecology. "These findings indicate that, even though patients present with the same disease stage at diagnosis, their survival outcomes differ."

The findings suggest that the 10-gene signature may have both predictive value and biological relevance that may be useful in treating patients.

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Wednesday, November 22, 2017
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Ovarian Cancer

This year in America Ovarian cancer will strike an estimated 25,500 women, and kill more than 14,000! Ovarian cancer remains the deadliest gynecologic malignancy and the fifth leading cause of cancer deaths among women in the United States.

What’s the problem? There is no early detector for Ovarian Cancer!

It’s been 25 years since a test for ovarian cancer was introduced to help diagnose this disease.
Should this get your attention, YES!
Should you do something about it? Yes!

I sailed along in life eating well, working out regularly, I didn’t smoke, didn’t have a drinking problem, only the occasional glass of wine. When one day I was told you have cancer. I have what! Wake up Sharon you have ovarian cancer.

It was found in the first stage, why? the early detection exams listed below found my cancer. I grant this there was a history in my family as my sister died from ovarian cancer. My question has always been this, I was examined for eight years before this was found.

Why can’t these tests be used as a regular, early detection tool for the discovery. All of the reports indicate that there is not substantial evidence to back this up. I am not an MD I am just a person who wants to do something about women suffering and dying unnecessarily. These women are not the only ones suffering, their family members are with them every step of the journey.

1a blood test of the serum CA 125 level (CA 125 is a high level of protein in the body)

2 transvaginal ultrasonography (TVU)

3 a pelvic exam

There is a new biomarker ...that has not been approved by the Food and Drug Administration for making a diagnosis of Ovarian cancer but only for monitoring the recurrence and progression of epithelial ovarian cancer. HE4 it will improve the ability to properly treat women in whom ovarian cancer has been diagnosed. The hope is it will be used in the future for an actual early detection in conjunction with the CA 125 serum.

Lets hope and pray that soon there will be the early detection break through we have been waiting for and end this nightmare.

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